Publications文献资料：

1.       Ko-Ting Chen et al. “Theranostic Strategy of Focused Ultrasound Induced Blood-Brain Barrier Opening for CNS Disease Treatment” Frontiers in Pharmacology, Feb 2019 Volume Article 86

2.       Tagedpjoseph Blackmore, et al. “Ultrasound Neuromodulation: A Review of results,-mechanisms and safety” Ultrasound in Medicine & Biology Volume 45, Number 7, 2019

3.       Robert F. Dallapiazza, et al. “Noninvasive neuromodulation and thalamic mapping with low-intensity focused ultrasound” Neurosurg Volume 128 • March 2018

4.       Raag D. Airan，et al. “Noninvasive Targeted Transcranial Neuromodulation via Focused Ultrasound Gated Drug Release from Nanoemulsions” Nano Lett. 2017, 17, 652−659.

5.       Zsofia I. Kovacsa et al. Disrupting the blood–brain barrier by focused ultrasound induc-es sterile inflammation” PNAS.1614777114

6.       Po-Chun Chu et al. “Focused Ultrasound-Induced Blood-Brain Barrier Opening: Association with Mechanical Index and Cavitation Index Analyzed by Dynamic Contrast-Enhanced Magnetic-Resonance Imaging” Scientific Reports | 6:33264 | DOI: 10.1038/srep33264

7.       Ellens, N. P. K., et al. “The targeting accuracy of a preclinical MRI-guided focused ultrasound system.” Medical physics 42.1 (2015): 430-439.

8.       Alison Burgess et al. “Focused ultrasound-mediated drug delivery through the blood–brain barrier” Expert Rev. Neurother. 15(5), 477–491 (2015)

9.       Burgess, Alison, et al. “Alzheimer disease in a mouse model: MR imaging–guided focused ultrasound targeted to the hippocampus opens the blood-brain barrier and improves pathologic abnormalities and behavior.” Radiology 273.3 (2014): 736-745.

10.    Diaz, Roberto Jose, et al. “Focused ultrasound delivery of Raman nanoparticles across the blood-brain barrier: Potential for targeting experimental brain tumors.” Nanomedi-cine: Nanotechnology, Biology and Medicine 10.5 (2014): 1075-1087.

11.    Nance, Elizabeth, et al. “Non-invasive delivery of stealth, brain-penetrating nanoparti-cles across the blood? brain barrier using MRI-guided focused ultrasound.” Journal of Controlled Release 189 (2014): 123-132.

12.    Oakden, Wendy, et al. “A non-surgical model of cervical spinal cord injury induced with focused ultrasound and microbubbles.” Journal of neuroscience methods 235 (2014): 92-100.

13.    Phillips, Linsey C., et al. “Dual perfluorocarbon nanodroplets enhance high intensity focused ultrasound heating and extend therapeutic window in vivo.” The Journal of the Acoustical Society of America 134.5 (2013): 4049-4049.

14.    Alkins, Ryan D., et al. “Enhancing drug delivery for boron neutron capture therapy of brain tumors with focused ultrasound.” Neuro-oncology (2013): not052.

15.    Alkins, Ryan, et al. “Focused ultrasound delivers targeted immune cells to metastatic brain tumors.” Cancer research 73.6 (2013): 1892-1899.

16.    Huang, Yuexi, Natalia I. Vykhodtseva, and Kullervo Hynynen. “Creating brain lesions with low-intensity focused ultrasound with microbubbles: a rat study at half a mega-hertz.” Ultrasound in medicine & biology 39.8 (2013): 1420-1428.

17.    Jord?o, Jessica F., et al. “Amyloid-β plaque reduction, endogenous antibody delivery and glial activation by brain-targeted, transcranial focused ultrasound.” Experimental neurology 248 (2013): 16-29.

18.    Scarcelli, Tiffany, et al. “Stimulation of hippocampal neurogenesis by transcranial focused ultrasound and microbubbles in adult mice.” Brain stimulation 7.2 (2013): 304-307.

19.    Meaghan A. O et al. “MRI-guided Disruption of the Blood-brain Barrier using Transcranial Focused Ultrasound in a Rat Model” Journal of Visualized Experiments, March 2012 | 61 | e3555 | Page 1 of 6

20.    Etame, Arnold B., et al. “Enhanced delivery of gold nanoparticles with therapeutic potential into the brain using MRI-guided focused ultrasound.” Nanomedicine: Nano-technology, Biology and Medicine 8.7 (2012): 1133-1142.

21.    Thévenot, Emmanuel, et al. “Targeted delivery of self-complementary adeno-associated virus serotype 9 to the brain, using magnetic resonance imaging-guided focused ultrasound.” Human gene therapy 23.11 (2012): 1144-1155.

22.    Staruch, Robert, Rajiv Chopra, and Kullervo Hynynen. “Hyperthermia in Bone Gener-ated with MR Imaging–controlled Focused Ultrasound: Control Strategies and Drug Delivery.” Radiology 263.1 (2012): 117-127.

23.    Burgess, Alison, et al. “Targeted delivery of neural stem cells to the brain using MRI-guided focused ultrasound to disrupt the blood-brain barrier.” PLoS One 6.11 (2011): e27877.

24.    Jord?o, Jessica F., et al. “Antibodies targeted to the brain with image-guided focused ultrasound reduces amyloid-β plaque load in the TgCRND8 mouse model of Alzhei-mer’ s disease.” PloS one 5.5 (2010): e10549.

25.    Leinenga, Gerhard, and Jürgen G?tz. “Scanning ultrasound removes amyloid-β and restores memory in an Alzheimer’ s disease mouse model.” Science translational medi-cine 7.278 (2015): 278ra33-278ra33.

26.    Wang, S., et al. “Noninvasive, neuron-specific gene therapy can be facilitated by focused ultrasound and recombinant adeno-associated virus.” Gene Therapy 22.1 (2015): 104-110.

27.    McDannold, Nathan, et al. “Temporary disruption of the blood–brain barrier by use of ultrasound and microbubbles: safety and efficacy evaluation in rhesus macaques.” Cancer research 72.14 (2012): 3652-3663.

28.    Treat, Lisa H., et al. “Improved anti-tumor effect of liposomal doxorubicin after target-ed blood-brain barrier disruption by MRI-guided focused ultrasound in rat glioma.” Ultrasound in medicine & biology 38.10 (2012): 1716-1725.

29.    Kinoshita, Manabu, et al. “Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood–brain barrier disruption.” Proceedings of the National Academy of Sciences 103.31 (2006): 11719-11723.

30.    Kinoshita, Manabu, et al. “Targeted delivery of antibodies through the blood–brain barrier by MRI-guided focused ultrasound.” Biochemical and biophysical research communications 340.4 (2006): 1085-1090.

31.    Burgess, Alison, and Kullervo Hynynen. “Drug delivery across the blood-brain barrier using focused ultrasound.” Expert opinion on drug delivery 11.5 (2014): 711-721.

32.    O’ Reilly, Meaghan A., and Kullervo Hynynen. “Ultrasound enhanced drug delivery to the brain and central nervous system.” International Journal of Hyperthermia 28.4 (2012): 386-396.

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